This modern photograph of a Sistine Chapel mosaic and is from Raphael's painting of the Madonna. Raffaello Sanzio was born in the small but artistically significant central Italian city of Urbino, which at the time was a cultural center that encouraged the Arts. Raphael is a leading figure of the Renaissance, best known for his "Madonnas" and his large mosaic compositions like this Photographic Detail from the Apostolic Palace in Vatican City.